In this video, Doctor Andrea Furlan answers 10 common questions about pregabalin:
Pregabalin is the generic name of a drug that we use to treat some types of chronic pain, in this video, i will answer the 10 most common 2. what is the correct dose of pregabalin? 4. which class of drug is pregabalin? work for my pain? 6. does pregabalin cause or cause weight gain? 8. can you drive or can 10. why
Pregabalin is not a controlled substance? 1) are pregabalin and gabapentin the same? pregabalin is c8 h17 no2 gabapentin is c9 h17 no2 and both are classified as gabapentinoids. i have another video that i talk about gabapentin. below you will see a link to that other video. which takes me to the next question. the maximum dose per day
Is 600 mg. we use it twice a day. so we usually start at low doses of 25 mg once a day we increase the dose slowly to give time to see if the person is not too sedated or dizzy. we usually don’t see any pain relief at lower doses. the person will notice the pain is before i continue, let me remind you that
This video is not intended to replace medical advice. it is for educational purposes only. you should contact your doctor for a proper diagnosis and treatment plan for you. in case of emergency, go to the nearest emergency department or call 911. nerve system and reduces the release sensations that arrive at the brain.
I explain what chronic pain is, you will remember that there are ascending pathways from the periphery to the brain, and descending well, the gabapentinoids, both pregabalin and gabapentin, they block the ascending pathways, so there are less electrical impulses arriving at the brain level, at the conscious brain,
Therefore, the brain will receive less bombarding in addition, pregabalin also mimics the endogenous neurotransmitter gaba. when the brain needs to slow down, to well, pregabalin can mimic gaba and supress thing if the person is having pain and anxiety, because pregabalin is an anticonvulsant medication, it has antiepileptic
Properties, for pain because its neuromodulation properties in the pain system pregabalin is an anticonvulsant medication, but we are using the term neuromodulator. so if someone asks me today what class of medication is pregabalin? i answer it is a neuromodulator. unfortunately not everyone with chronic if
They don’t see at least 30% pain relief, then it is not working for them. yet. a lot of patients have to stop early, then, it could be that you didn’t try for long enough. i tell patients that when you get to the therapeutic dose, of at least 300 mg per day, then they need to wait between 2 to 6 months
Twice a day. i know some patients don’t like to take pregabalin in the morning because of the sleepiness or dizziness. but if they only take once a day, then there is no way to know have is not responsive to pregabalin. summarized 45 randomized controlled trials of pregabalin for neuropathic pain in adults. post-herpetic
Neuralgia painful diabetic neuralgia you know what their conclusions were? in postherpetic neuralgia, painful unclassified post-traumatic neuropathic pain and inadequate evidence of efficacy in central neuropathic pain there is another cochrane review of pregabalin for fibromyalgia that was updated in 2016. authors of the review looked
At the efficacy they found 1 study of 263 patients that benefit of pregabalin compared to placebo. you see that with increased dose the proportion case at least 30% pain intensity reduction, so, they concluded pregabalin 300 to 600 mg produces a major reduction in pain intensity over 12 to 26 weeks with tolerable adverse
Events for a small proportion of people (about 10% more than placebo) with moderate or severe pain due to fibromyalgia. improvements in other symptoms, quality of life, and function. included trials that compared pregabalin fibromyalgia. they found results are similar 6) does pregabalin cause any damage to the
Liver or kidneys? to the liver or kidney, even if the person needs to use pregabalin for the rest of their lives. problem before they start using pregabalin because their dose needs to be adjusted. they will require a lower dose than people who do not have a liver or kidney function problem. 7) will pregabalin make you
Sleepy or cause weight gain? of pregabalin are dizziness, somnolence, weight gain, leg swelling, and dry mouth. but there are many other potential adverse effects 8) can you drive or can you take alcohol with pregabalin? dizzy and sleepy you should not be driving a car or operating any heavy equipment. you could
Cause injury to yourself and others. 9) is pregabalin good for anxiety? pregabalin has sedating effects, and those can be helpful to people who suffer form anxiety disorders. they are used in combination with other anxiolytic medications however, it is important to remember that if you stop taking your daily duloxetine your
Body include anxiety, insomnia and headache. but this is not the same thing as being addicted to pregabalin. there is no such thing as addiction to pregabalin. the person may develop dependence, the same way that people can develop physical dependence on thyroid hormones or blood pressure medications. if they stop
Any of those medications abruptly, they have withdrawal symptoms. it does 10) why pregabalin is not a controlled substance? as i explained before, there is no risk of i know people may abuse pregabalin, but people can also abuse acetaminophen, anti-inflammatories or anti-nausea medications. it doesn’t mean so,
I hope these answered your 10 top questions about pregabalin. and don’t forget to subscribe to this channel and turn on the notifications button.
Transcribed from video
10 Questions about pregabalin (LYRICA) for pain: uses, dosages, and risks By Dr. Andrea Furlan
