Catedra: Ingles Medico
Hi my name is jose sarsosa i am going to evolve to a pixel van to prevent by non-strong members in passion with cancer definition a pixel bank is antiqual and used to try and to prevent blood clots and to prevent a stroke in people with arterial fibrillation specifically it is used to prevent blood loads following hypernear replacement and those which are
Story of prior lots it is using an alternative to warfarin and does not require monitoring by block tests it is taken by much patients with cancer have an increased risk of venous thromboembolism but parenteral thromboprophylaxis is not routinely recommended in practice guidelines because the absolute risk reduction is modest and parenteral thromboprophylaxis
Is associated with an increased risk of major bleeding as well as the inconvenience of daily injections could a direct oral anticoagulant such as apixaban used as a thromboprophylactic agent in patients with cancer offer advantages over parenteral agents particularly with regard to convenience the randomized placebo-controlled double-blind avert trial included
Ambulatory patients with cancer who were at intermediate to high risk for venous thromboembolism with a karana score of two or more the karana score has been validated to identify patients with cancer who are at elevated risk for thromboembolism the trial patients were randomized to apixaban for thromboprophylaxis before chemotherapy or to placebo before chemotherapy
The primary outcome was objectively documented venous thromboembolism over a period of 180 days in a modified intention to treat analysis venous thromboembolism occurred in 4.2 percent of the 288 patients in the apixaban group and 10.2 percent of the 275 patients in the placebo group the number needed to treat to prevent venous thromboembolism was 17. the main
Safety outcome was major bleeding major bleeding occurred in 10 patients in the apixaban group and five patients in the placebo group the authors conclude that a pixaban at the initiation of chemotherapy resulted in significantly lower rates of venous thromboembolism than did placebo among intermediate to high-risk ambulatory patients with cancer the rate of major
Bleeding episodes was higher with a pixaban than with placebo full trial results are available at nejm.org five application in medicine first to lower the risk of a stroke and embolus in passion with no power lateral fibrillation second the vented thrombosis dvt preventivity might lead to pulmonary embolism in a inaudible replacement to harry potter three
Treatment of both dbt and b four to reduce the risk of recurring dvt and p after initial therapy pros and cons plus the use the direct and equivalence are thromboprophylaxis and hence in fashion which cancer can offer advantages over parenteral hands including root wrote the of administration convenience and cons counts application can increase the risk of
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Of one per two house and popular population estate 10.27 venus from wembolis affects the population over 40 years of a with the ration of 1.3 to 1 in men and women respectively the most recurrent figure report by ecuador scroll the a and ec are 4 2004 we show 220 24 cassettes of peat nationwidth for a population of 10.8 10.00 evidence um conclusion
Apixaban therapy results in us in a significantly lower rate of venus thromboembolis that did the placebo among intermediate to high rates ambulatory passion which concerned how how hair extracting chemotherapy the right of minor bleeding fsu episodes were higher but we know that there’s so many folks in the octogenarian plus group and we also know that a lot
Of folks are being fearful of treating them with therapeutic anticoagulation so and then if you do that which one thank you
Transcribed from video
APIXABAN TO PREVENT VENOUS THROMBOEMBOLISM IN PATIENTS WITH CANCER By Jose Luiis
