Catedra: Ingles Medico
Hi my name is jose sarsosa i’m going to about two a pixel and two paraben benefits in fashion with cancer definition a pixel is antiqual and used to try and prevent blood clots and to prevent a stroke in people with ultrafibulation specifically it is used to prevent blood clots following import knee replacement and in with a story of prior plots it is used
An alternative to warfarin and does not require monitoring by blood threats it is taken by much patients with cancer have an increased risk of venous thromboembolism but parenteral thromboprophylaxis is not routinely recommended in practice guidelines because the absolute risk reduction is modest and parenteral thromboprophylaxis is associated with an increased
Risk of major bleeding as well as the inconvenience of daily injections could a direct oral anticoagulant such as apixaban used as a thromboprophylactic agent in patients with cancer offer advantages over parenteral agents particularly with regard to convenience the randomized placebo-controlled double-blind avert trial included ambulatory patients with cancer
Who were at intermediate to high risk for venous thromboembolism with a karana score of two or more the karana score has been validated to identify patients with cancer who are at elevated risk for thromboembolism the trial patients were randomized to apixaban for thromboprophylaxis before chemotherapy or to placebo before chemotherapy the primary outcome was
Objectively documented venous thromboembolism over a period of 180 days in a modified intention to treat analysis venous thromboembolism occurred in 4.2 percent of the 288 patients in the apixaban group and 10.2 percent of the 275 patients in the placebo group the number needed to treat to prevent venous thromboembolism was 17. the main safety outcome was major
Bleeding major bleeding occurred in 10 patients in the apixaban group and five patients in the placebo group the authors conclude that a pixaban at the initiation of chemotherapy resulted in significantly lower rates of venous thromboembolism than did placebo among intermediate to high-risk ambulatory patients with cancer the rate of major bleeding episodes was
Higher with a pixaban than with placebo full trial results are available at nejm.org five application in medicine first to lower the risk of stroke and embolism in people with nonviolent atrial fibrillation second the vented thrombosis dvt prevention dvt must lead to pulmonary embolism ana or p replacement to harry potter 3 treatment of both dbt and p four
To reduce the risk of recurring dbt and p after initial therapy pros and cons pros the use of lyric direct anticoagulant and thromboprophylaxis are against a bipartisan which cancer can offer advantages over parental enhanced including right of administration convenience and cuts counts first a pixel can increase the risk of beating which might be serious
Potential battle second when spinner epidural and instead of punctural is used passion how how are being treated with anti-thrombotic complications are the risk for developing a hematoma which can cause long-term or permanent permanent paralysis so you set a plate in ecuador statistics in ecuador are scorned however an incidence of one per 2000
Population estimated 10.27 when those thromboembolis affect the population over 40 years of age with the ration of 1.3 to 1 in a man in men and women respectively the most reco current figure report by ecuador strode the a and eco are formed to 2004 which show 100 cows of peat nationwidth for a population of 10 point age 10.00 habitants conclusion a pixelman
Therapy result in a significantly lower rate of venus thromboembolis that is placebo among internality to to right to high reach ambulance ambulatory passion which cancer how however striving chemotherapy the rate of myer blading epc was higher with a pixelman that which placebo uh folks in the octogenarian plus group and we also know that a lot of folks are
Being fearful of treating them with therapeutic anticoagulation so and then if you do that which one thank you
Transcribed from video
APIXABAN TO PREVENT VENOUS THROMBOEMBOLISM IN PATIENTS WITH CANCER By Jose Luiis
