June 1, 2023

Hello mandy and lauren here today we’re your nurses and we’re going to talk to you about your prescription apixaban which is also known as eliquis apixaban is a blood thinner anticoagulant meaning that it thins the blood clots do not occur apixaban acts as a selective reversible site inhibitor a factor xa it inhibits both the free and the bound factor apixaban does

Not affect platelet aggregation directly but it does inhibit thrombi induced platelet aggregation it decreases thrombin generation and thrombus development because of this apixaban is used for the treatment and prevention of thromboembolic events apixaban is taken to decrease the risk of stroke or systemic imple ism and people who have nonvascular atrial fibrillation

A type of irregular heartbeat apixaban is used only to treat and reduce the risk of reoccurrence of deep vein thrombosis or pulmonary embolism apixaban may be given to prevent the development of deep vein thrombosis following a knee or hip replacement doing so will reduce the risk of a pulmonary embolism apixaban is usually taken twice a day with or without food

If you’re unable to swallow a tablet apixaban tablets can be crushed and mixed with water dextrose in water or apple juice a pixabay can also be crushed and mixed in applesauce if you need to crush a pick seban and mix it to ensure that you’re taking this medication you must do so immediately if you use an ng tube or a nasogastric tube you can also take a pic seban

By crushing it and mixing it with 60 milliliters of water or dextrose in water and promptly administer it through the tube if you get stuck or confused don’t worry your trusted nurse is here to help depending on what you are taking a picks bamforth there are different instructions if you are taking a pick seban for the reduction of stroke or systemic embolism

Risk for atrial fibrillation the usual dose is 5 milligrams twice a day for those older than 80 years of age weighing less than 60 kilograms we’re having a serum creatinine greater than one point five milligrams per deciliter your health care provider may reduce the usual daily dose to 2.5 milligrams twice a day if you are currently taking a strong inhibitor at

Both cyp3a4 and g glycoprotein your health care provider may reduce the usual daily dose to 2.5 milligrams twice a day if you have renal impairment the usual dose may be either 2.5 or 5 milligrams twice a day if you’re taking a pic seban for prevention of deep throat vein thrombosis also known as dvt following a near hip replacement your healthcare provider will

Start you on 2 point 5 milligrams twice a day within the first day following your surgery for a hip replacement you will continue apixaban for 35 days if you had a knee replacement you will continue apixaban for 12 days if you’re taking it for a dvt or pulmonary embolism your dosing will be higher for the first week the usual dose is 10 milligrams twice a day for

One week followed by five milligrams twice a day thereafter if you are taking a picks ban for reduction in the risk of development of another dvt or pulmonary embolism usual dose is 2.5 milligrams for at least six months after your last dvt or pulmonary embolism it’s important that you take this medication as prescribed if you forget to take a dose take it as soon

As you remember but if it’s also time for your next dose skip the missed dose and take only the one that is scheduled at that time do not take two doses at the same time do not stop taking this medication without talking to your health care provider first stopping apixaban can increase your risk of stroke deep vein thrombosis and pulmonary embolisms notify your

Health care provider of any surgery medical or upcoming dental procedures your health care provider will let you know if and when you should stop taking this your medication and when you should start taking it again so what about side effects the most common side effect of the medication is bleeding so you might notice some minor you’re bruising when you brush

Your teeth or minor bruising on your skin notify your health care provider or go to the emergency department if you have any signs of major bleeding so this might include seeing blood and urine or stool coughing up blood or bleeding that will not stop you should also go to the emergency department if you have a severe allergic reaction while taking a pic seban

And that can lead to anaphylaxis which is a life-threatening reaction it is very important to tell your health care provider or pharmacist of any medications that you currently take these include all prescription medications any medications that are over-the-counter and vitamin and herbal supplements you should also notify your health care provider or pharmacist

Before taking any new medications so that he or she can check for any drug interactions you should store your medication at room temperature away from young children and animals so we don’t advise taking a pic seban if you’ve ever had a severe allergic reaction to a picc seban including anaphylaxis do not take a pic seban if you have active pathological bleeding

Severe hepatic or liver impairment have a prosthetic heart fell currently have a pulmonary embolism that is hemodynamically unstable or requiring thermolysis or pulmonary embolectomy or also if you’re taking a medication that’s a strong dual inducer of the cyp3a4 and glycoprotein systems notify your health care provider before taking a pic seban if you have renal

Or kidney impairment or having surgery have an increased risk for thrombosis following discontinuation if you are planning to have a procedure that uses neuro axial spinal anesthesia or spinal puncture with an indwelling epidural catheter drugs that affect hemostasis or of a history of traumatic or repeated spinal punctures or if you have a spinal deformity your

Healthcare provider will discuss it if apixaban is right for you so before tate starting a picc seban you should let your healthcare provider know if you’re taking any anticoagulants aspirin clopidogrel dick a girl or prasugrel fibrinolytics nsaids ssris or ssris because these can increase your risk of bleeding also concurrent use of a strong inhibitor of both cyp3a4

And p-glycoprotein enzyme systems which include itraconazole ketoconazole and rid o nevere may increase your apixaban levels and increase your risk of bleeding you your providers therefore my decrease your dose of a picc seban to 2.5 milligrams twice a day your healthcare provider might also avoid starting you on a picc seban if you are taking cyp3a4 enzyme system

Drugs and g like p-glycoprotein system drugs that include carbamazepine phenytoin and rifampin because these can decrease your apixaban levels and increase your risk of thrombosis concurrent use of st. john’s wort is a strong doing juicer of both of those enzymatic systems and should also be avoided as it can depreciate pixabay in levels and again increase your risk

Of thrombosis the safety of a picc span and children under 18 years old has not been established sorry kids we won’t be prescribing you this drug talk to your health care provider if you plan to become pregnant or suspect you are currently pregnant the use of apixaban during pregnancy should be cautioned the use of pregnancy category c medications have been known

To cause or may be suspected of causing harmful effects on the human fetus or neonate without causing a malformation these effects may or may not be reversible apixaban should only be used here in pregnancy if the potential benefit outweighs the possible risk to both the mother and the fetus that’s something we can determine together so breastfeeding mothers should

Also be cautious when taking a pick seban if you are taking a picks ban at the hospital your nurse will assess you for symptoms of stroke deep vein thrombosis pulmonary embolus and peripheral vascular disease throughout the day so once you go home the nurse at your health care providers office will continue to assess you for these symptoms periodically while you’re

On a pic seban and if anything is recognized will update your provider as changes in medication may need to occur your nurse will also assess for pixiv and toxicity and overdose as an antidote or reversal agent is not currently available the effects of apixaban toxicity will persist for 24 hours find the last dose of the pics of an if you think you’re experiencing

Signs of toxicity or overdose at home call the poison control center or go to your local emergency department oral activated charcoal will decrease the absorption of a picc seban lowering the plasma concentrations other agents and emo dialysis do not have a significant effect knowing these important points about your picks the ban will keep you safe and allow you

To receive the full benefit from the medication thank you for taking the time to watch our video please contact us with any questions and talk to her health care provider about a picc span today

Transcribed from video
Apixaban By Lauren Hamaty