February 8, 2023

In this video, I’m gonna tell you what are the important side effects and why you should be careful if you’re on metformin, and also some tips and tricks to prevent those nasty side effects. The number one side effect of metformin is gastrointestinal side effects. Examples include diarrhea, Nausea, Flatulence, Dyspepsia, Vomiting, and abdominal pain. The second side effect is Lactic Acidosis. The third side effect is Vitamin B12 deficiency.

Hey what’s up guys! welcome back to dr. says. have  you recently started on metformin by a doctor for   for long and you’re not sure what is it anyway?   today, i’m going to tell you what to look out  for if you’re on metformin and if you stay till   the end of the video i’ll share with you some  tips you can do to avoid some side

Effects.   first, it decreases glucose production from the  liver. second, it decreases intestinal absorption   sensitivity which in turn increases glucose uptake   by your organ and tissue. moving on to the side  effects. the number one side effect of metformin   include diarrhea, nausea, flatulence, dyspepsia,  

Vomiting, and abdominal pain. it usually occurs  during the initiation of the therapy. however,   a minority of people do experience these symptoms  after several weeks into the therapy. stay till   the end because i promise i’ll share with you  the tips to prevent these side effects. the   second side effect is lactic

Acidosis. metformin  is able to increase the acid level in your body   by increasing a substance known as lactic acid.  in general, you do not need to worry about this   complication and can safely take metformin unless  you have a bad kidney, liver, or heart function to   begin with. number three, vitamin b12 deficiency. 

Long-term use of metformin has been associated   with vitamin b12 deficiency which in turn leads  to anemia and neuropathy i.e nerve problems. you   vitamin b12 or increased intake of calcium as   proven by this study. they are taking a total of  1.2 grams of calcium per day. if the deficiency   is severe enough, one can

Also take a thousand to  two thousand micrograms of oral vitamin b12 daily.   moving on to the contraindications. number one,  severe renal impairment. you should not be on   metformin if a kidney function measured in egfr  is less than 30. if your egfr is between 30 to 45   to a maximum of 500 milligrams twice daily  

With close monitoring of your kidney function.  number two, severe hepatic impairment. if you have   liver failure or cirrhosis metformin increases  the risk of lactic acidosis. number three,   severe unstable heart failure. again, a very poor  heart function leads to poor tissue perfusion.   therefore once again increases the

Risk of lactic  acidosis. now as promised here are some valuable   tips if you are on metformin. if you experience  gi symptoms here are some ways to prevent them.   number one, avoid rapid dose escalation. you may  start with 500 milligrams once or twice a day   and then slowly increase to thousand milligrams  once or

Twice a day, your stomach will thank you   for that! number two, use extended formulations.  an example is metformin xr. you are required to   therefore less frequency, fewer side effects.   can do this on both metformin or metformin xr.   by taking it just before bedtime the majority  of my patients did not experience the

Dreaded   need a rest too! number four, stop metformin   if you are seriously ill or unwell. many of times  i’ve encountered patients who are unwell for days   their metformin. this is dangerous as you have   acid levels. when you are ill and unwell your   blood acid level is naturally high. therefore  metformin

Will only exacerbate your condition   if it’s severe enough it is potentially   life-threatening. so there you have it guys! thank  you for watching and if you miss the rest of this   diabetes series you can proceed to click on the  link on the screen now. stay safe, stay healthy   for more content like this in the future!

Transcribed from video
BE CAREFUL If you're on METFORMIN | Metformin side effects | Metformin TIPS | How to take metformin By Doctor Says