January 26, 2023

In this episode, I discuss a medication commonly used to treat anxiety known as buspirone (Buspar).

Everybody welcome back to another episode of drug talk as always i’m your host gary campbell today we’re going to be discussing a medication known as a buspirone with a brand name of buspar before we get into the medication itself just keep in mind that this channel is for information purposes only and not to be used as a source for recommendations for your

Personal healthcare abuse perón is an agonist on the 5h t1a receptor and it’s most commonly used for anxiety official indication would be that it’s used for short-term symptomatic relief of excessive anxiety in individuals who have generalized anxiety disorder it can also be used as an alternative to benzodiazepines this would be most commonly seen when sedation or

Psychomotor impairment may be dangerous for the individual using the medication this could also be beneficial in individuals who have a history of substance abuse miss perrone is occasionally seen used to treat obsessive-compulsive disorder it can be used in depression to help augment the effects of antidepressants is occasionally seen in social phobias although

The evidence is contradictory to whether or not it is truly effective individuals with premenstrual dysphoric disorder may benefit from buspirone it can be used to help treat agitation or aggression antisocial behaviors as well as sexual performance disorders lastly it is sometimes used to help alleviate the bruxism that may be caused by ssris before somebody

Wants to start using buspirone there are some precautions that they must be made aware of one is that there’s no cross tolerance between goose barone and benzodiazepines buspirone will not help alleviate benzodiazepine withdrawal and when switching from a benzodiazepine to buspirone the buspirone should actually be added while the patient is still tapering the

Benzodiazepine buspirone does not have anticonvulsant activity and has not been studied in patients with seizures it is not recommended for patients with seizures now once somebody is made aware of the precautions and they start using the medication typically they would start off on a dose of five milligrams taken twice or three times daily this dose can then

Be increased in increments of 5 milligrams every 2 or 3 days to a maximum of 60 milligrams daily the usual fare buta dose for patients is about 20 to 30 milligrams a day or 10 to 15 milligrams twice a day it should be noted that doses up to 90 milligrams have been used typically in patients with severe depression that have a lot of anxiety as a symptom of their

Depression unfortunately with buspirone it does take some time to work it can be 2 to 4 weeks before you really notice that anti-anxiety effects set in buspirone is not effective when used on an as-needed basis it must be taken consistently the last thing to note here is that we decrease the dose by 25 to 50 percent in individuals who have a creatinine clearance

Less than 10 mils per min as with all medications there are some adverse reactions or side effects that people may experience while using buspirone so i’ll include some of those here for you now before i left off the side effects however i just want to make a note that buspirone causes little sedation and it does not impair psychomotor or cognitive function now

About 6 percent of people experience headaches while 12% experience dizziness lightheadedness happens to about 3 percent of people and nervousness happens to 5% about 2% of people may have this sense of excitement when they use the medication and fatigue numbness as well as gi upset happens in less than 10% of individuals miss perrone does have the ability to bind to

Central dopamine receptors and this can cause some side effects occasionally although not substantiated by trials such as pseudo parkinsonism akathisia as well as dystonia again i will say that these side effects are not substantiated by clinical trials however there is a restlessness that is sometimes reported upon initiation of buspirone and people do think that

This is caused by its dilton manner jerk or nor adrenergic effects miss perrone does have the ability to cause mania when used in individuals who do have bipolar disorder this seems to happen more commonly in the elderly population as well as people using high doses of this medication and lastly there have been cases of priapism reported that’s already discussed

Today with buspirone or buspar as always i’m thankful that you took the time to comply and watch one of my videos if you found the information valuable and you’d like to help me grow this channel you can like the videos share the videos or most importantly subscribe to the youtube there’s also some links in the description you can check them as well that’s it for today take care

Transcribed from video
BUSPIRONE (BUSPAR) – PHARMACIST REVIEW – #42 By Drug Talk