November 29, 2022

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The representative medication in the loop diuretics is furosemide furosemide is very potent that it can induce diuresis on patient who does not respond to other diuretics or with renal impairment in addition furosemide is prompt and has a short duration of action making diuresis predictable it can be given orally or intravenously furosemide pharmacologically is a

Loop diuretic therapeutically it is an antihypertensive furosemide affects almost the entire nephron including proximal and distal convoluted tubules yet most importantly it acts on ascending loop of henle it interferes the mechanism of sodium potassium chloride co-transporter and sodium chloride transporter leading to excretions of these three cay ions follows

The diuresis furthermore it also causes loss of calcium and magnesium the therapeutic results of using furosemide are decreased cardiac workload and lowered blood pressure considering the therapeutic effects of furosemide edema and hypertension are the indications for it however its action mechanism leads to electrolyte imbalances dehydration and hypovolemia

Or worse acute hypovolemic shock furosemide is a very potent prompt diuretic the induced dehydration could further lead to hypotension and electrolyte imbalances can lead to severe hypokalemia hyponatremia hypomagnesemia hypocalcemia hyperglycemia hyperurexemia and gout elderlies are more susceptible to effects of dehydration and electrolyte imbalances both

Can be fatal while adverse effects described earlier are commonly shared among diuretics more or less being a loop diuretic furosemide is autotoxic in other words autotoxicity is a major adverse effect furosemide can lead to reversible or permanent hearing loss risk for autotoxicity increases when using furosemide inappropriately or in combination with other

Autotoxic medications or in patients who have severe renal impairment patients with severe renal impairment aneuria or patients who are sensitive to furosemide should not take this medication furosemide is used in pregnancy only if benefits outweigh the risk there is no well-controlled study to support its usage in pregnancy also furosemide is excreted into

Breast milk therefore special caution should be taken when using furosemide during breastfeeding it is found that using furosemide in early weeks of life on premature infants increases risk for persistent patent ductus arteriosus teach the client the signs and symptoms and management of the adverse effects teach the female clients to report pregnancy and

Decision on breastfeeding teach the client to take diuretics in the morning and early afternoon to avoid bacteria teach the client to avoid exposure to sun teach the client to monitor blood pressure heart rate body weight regularly teach the client prevention of orthostatic hypotension and other safety measures monitor elderly patients more closely because

They are more susceptible to fluid and electrolyte imbalances teach the patient to call 9-1-1 if experiencing symptoms of heart attack or hypovolemic shock monitor fluid and electrolyte status as well as renal function use supplement of potassium or magnesium as needed teach the client to monitor ototoxicity which can manifest as hearing loss or vertigo when

Giving furosemide intravenously note that iv solution should be clear and colorless discard solution if it’s cloudy or with sediments iv solution should be used within 24 hours after preparation discard it if past 24 hours do not mix furosemide with other solution use separate tubing set and always flush the iv catheter with saline before and after medication

Administration administering furosemide fast via iv route increases risk of auto toxicity therefore mind the rate administer furosemide over one to two minutes if iv push and administer furosemide at rate not faster than 4 milligram per minute if iv infusion using furosemide with aminoglycoside antibiotics and cisplatin can increase risk of autotoxicity and for

Terrorism b corticosteroids corticotropin metabolism can increase risk of hypokalemia of furosemide furosemide can cause hyperglycemia therefore it can decrease the hypoglycemic effect of anti-diabetics when using with antihypertensives there will be an additive effect to lower blood pressure even more furosemide can cause hypokalemia therefore it increases

The toxicity effect of cardiac glycoside and neurotransmitter blockers must closely monitor the potassium level furosemide can also increase toxicity of lithium because it decreases the excretion of lithium leading to accumulation of lithium monitor lithium level nsaids can affect synthesis of renal prostaglandin therefore it can decrease the diuretic effect

Of furosemide phonitoine can decrease diuresis of furosemide when using with propranolol furosemide can increase propranolol level leading to hypotension must monitor patients closely if patients are using these two medications furosemide can increase toxicity of salicylates so crop fate can reduce diuretic effect use these medications apart by two hours

Discourage the client to use aloe vera with furosemide because aloe vera can increase effect bayberry blue kohash cayenne aphedra ginger american ginseng and cola can worsen hypertension it is recommended not to use these herbs with furosemide together licorice can worsen hypertension and cause rapid potassium loss instruct the client to avoid taking licorice

With furosemide if possible it is highly recommended for patient to take furosemide on an empty stomach because any food can interfere with furosemide’s already poor absorption leading to low furosemide level and decrease diuresis effect exposure to sun can increase photosensitivity reaction advise the client to avoid exposure to sunlight by wearing light

Colored long-sleeve top and pants and sunscreen thank you for spending time with me i look forward to seeing you again you

Transcribed from video
Loop Diuretic- Furosemide By Apricad Courses of Nursing