February 8, 2023

Pharmacist review of side effects of Losartan, how Losartan works as well as the uses of Losartan.

Hello folks welcome back if you’re new around here my name is koiku and i’m a pharmacist today i’m going to be briefly reviewing the medication losartan we’re going to take a look at its description and uses we will take a look at how it works and the common dosing as well as some side effects before we delve any further though i just wanted to mention that

This review is for informational purposes only and is not intended to be a substitute for medical advice from your physician so losartan belongs to a class of medications called angiotensin ii receptor antagonist or blockers sometimes shortened as arbs or arbs they are primarily used in the management of hypertension diabetic nephropathy where they are given

To protect the kidneys of people who have diabetes it is used in heart failure as well as a prevention of prophylaxis for stroke losartan and other medications in that class work by blocking the receptors on which angiotensin two weeks now angiotensin ii is a hormone produced by the body it’s a very potent vasoconstrictor or in other words it causes the blood

Vessels to constrict constricted blood vessels mean that there is an increased resistance to blood flow which results in an increase in the blood pressure blocking the receptors on which angiotensin ii acts therefore results in the relaxation of blood vessels and consequently less resistance to blood flow which ultimately leads to a reduction in blood pressure

Now angiotensin ii also stimulates aldosterone secretion from the adrenal gland aldosterone causes an increase in salt and water reabsorption into the bloodstream from the kidney thereby increasing blood volume which ultimately leads to an increase in blood pressure thus by blocking the effects of angiotensin ii losartan decreases aldosterone secretion and

Consequently causes a reduction in blood pressure the dose ranges anywhere between 25 milligrams to 100 milligrams daily depending on what is being treated and the individual in question the typical dose though is generally about 50 milligrams daily it is typically taken once a day but every so often you’ll find that it is given twice a day if it provides better

Coverage that way with respect to side effects losartan is generally well tolerated and side effects are generally mild lucitan and other arbs offer a key advantage over a similar group of medications called ace inhibitors which are very well known they usually end in il like lisinopril i think that’s the most popular one in that group now that group is typically

Noted for two key side effects a dry cough and angioedema the good thing is that lusatan is associated with a very low incidence of both of these side effects so this makes los satan a very good substitute for people that have experienced these side effects while taking its inhibitors like lycinropril some of the reported side effects include abdominal pain back

Pain muscle cramps and with muscle cramps one of the things about losartan is that it has the potential to increase your potassium levels so your doctor will probably monitor those levels and i specifically mentioned that because an increase in your potassium levels can sometimes lead to muscle cramping other reported side effects include dizziness insomnia

Headache and fatigue this list is obviously not exhaustive but like i said earlier low saturn is generally very well tolerated the overall incidence of adverse reactions in one particular study that involved about four thousand patients who had been taking low certain for periods greater than six to 12 months found no relevant differences between the adverse

Experience profile for people that were taking los certain and a placebo but like all other blood pressure medications or any medication in general if you experience any adverse effects would be a good idea to discuss with your doctor do not stop taking it abruptly or do not start taking it without talking to your doctor so that’s a high level overview of low

Certain i hope you found it useful if you did please give it a thumbs up share with somebody else who may find it useful and if you haven’t done so already please do also subscribe to the channel if you found this video beneficial thank you so much and i’ll catch you on the next one

Transcribed from video
LOSARTAN Side Effects | How LOSARTAN Works | Pharmacist Review of Losartan By Pharmacist Conversations