December 8, 2022

Section 1.6 interactive assignment objective 1 to determine if tapiramate is an effective treatment for alcohol dependence researchers conducted a 14-week trial of 371 men and women aged 18 to 65 years diagnosed with alcohol dependence in this double-blind randomized placebo-controlled experiment subjects were randomly given either 300 milligrams of topiramate

Or a placebo now the top pyramid 183 subjects placebo had 188 subjects daily along with a weekly compliance enhancement intervention the variable used to determine the effectiveness of the treatment was self-reported percentage of heavy drinking days results indicated that topiramate was more effective than placebo at reducing the percentage of heavy drinking days

The researchers concluded that topiramate is a promising treatment for alcohol dependence and we’re going to complete parts a through f first question is what does it mean for the experiment to be placebo-controlled so let’s take a look at the definition of a placebo-controlled now a placebo is an innocuous medication such as a sugar tablet that looks tastes and

Smells like the experimental medication in some experiments such as when the effectiveness of a medication is being studied a placebo treatment or medication is given to the subjects in the in the control group using a placebo treatment enables blinding to be used okay now the answer is going to be c because the experiment will have a control group that takes

A placebo which is an innocuous medication such as a sugar tablet this control group serves as a baseline treatment that can be used to compare to the group that is actually taking the medication so therefore the answer again is in this case c for this one next question what does it mean for the experiment to be double blind why do you think it is necessary

For the experiment to be double blind first we’re going to explain what it means for the experiment to be double blind so let’s take a look at the definition for that okay so in a double-blind experiment neither the subject nor the researcher in contact with the subject knows which treatment is received when the researcher also does not know which treatment is

Received it helps ensure that they observe each group the same way so therefore b in this case neither the subject nor the researcher knows which treatment the subject is receiving so in this case here again neither the subject nor the receipt researcher knows which treatment the subject is receiving the next question says why do you think it is necessary for

The experiment to be double blind well the experiment is double-blind so that the subjects receiving the medication do not behave differently and so the individual monitoring the subject does not treat those receiving medication differently from those receiving the placebo so therefore that would be the answer for that so in this one that would be the same here

The experiment is double blind so the subjects receiving the medication do not behave differently and so the individual monitoring the subjects does not treat those receiving medication differently from those receiving a placebo part c it says what does it mean for the experiment to be randomized okay let’s take a look here so what does it mean well randomized

Design means that each subject is randomly assigned to a treatment so therefore here it says that it means that the subjects are randomly assigned to take either topper topper to pyramid or the placebo so therefore it means the subjects are randomly assigned to take either topiramate or the placebo part d what is the population for which this study applies and

What is the sample okay well let’s go over the definition well the entire group to be studied is called the population an individual is a person or object that is a member of the population being studied a sample is a subset of the population that is being studied so we would say that the population is all 18 to 65 year olds with alcohol dependence the sample

Is 371 men and women aged 18 to 65 years diagnosed with alcohol dependence so therefore again the population is all 18 65 year olds with alcohol dependence and the sample is 375 71 men and women aged 18 and 65 years diagnosed with alcohol dependence okay let’s take a look at e what are the treatments well an experiment is controlled as a control study conducted

To determine the effective varying the effect varying one or more explanatory variables or factors has on a response variable so any combination of values of the factors is called a treatment so in this case 300 milligrams of topiramate or a placebo daily and a weekly compliance enhancement intervention would be the treatment so therefore again 300 milligrams

Topiramate the placebo daily and a weekly compliance enhancement intervention okay last question what is the response variable okay now in an experiment the goal is to determine how varying the amount of an explanatory variable affects the value of a response variable the response variable is the outcome of a study which is a variable you are trying to predict

In this case here is the percentage of heavy drinking days so therefore that represents the response variable so therefore we would say that the percentage of heavy drinking days is the response variable

Transcribed from video
Math 14 1.6 Objective 1: Describe the Characteristics of an Experiment By Fiorentino Siciliano