February 8, 2023

Hello class today laura and i will be talking about a diuretic called furosemide furosemide is the generic name of this drug and its train name is lasix as mentioned earlier furosemide is a diuretic a drug type that adjusts the volume and or composition of body fluids it is specifically a loop diuretic which plays a part in its mechanism of action the indications

For a diuretic like furosemide are edema due to heart failure hepatic impairments which is impaired liver function or renal failure and hypertension which is high blood pressure diuretics in general blocks sodium reabsorption this sends more sodium ions to the urine which causes water and other ions such as chloride magnesium potassium and calcium to be

Excreted by the kidney the increased excretion of fluids from the kidney results in a larger volume of urination which is known as diuresis this is especially true for furosemide because it is a loop diuretic loop diuretics inhibit the reabsorption of sodium and chloride from the loop of henline and the distal renal tubule which induces large increases in urine

Output for the pharmacokinetics of furosemide 60 to 67 percent of the dose is absorbed in both oral and i am administrations of it it is distributed to most tissues crosses the placenta can be secreted in breast milk and 95 bound to plasma proteins small amounts of it are metabolized by the liver and some of the drugs is excreted by the kidneys unchanged in the

Urine furosemide can be administered orally and through iv and iron injections dosage ranges for all administration is initially 20 to 80 milligrams a day as a single dose though it may be repeated in six to eight hours the dose can also increase by 20 to 40 milligrams every six to eight hours until there is a desired response individuals with hypertension can

Have an oral dose of 40 milligrams twice a day initially which can be further adjusted based on response i im and iv routes have doses of 20 to 40 milligrams that can be repeated in one to two hours and increase by 20 milligrams until response is obtained oral furosemide medication has an onset of 30 to 60 minutes a peak of 1 to 2 hours and a duration of 68

Hours an im injection onset is 10 to 30 minutes and its duration is 4 to 8 hours but its peak is unknown iv administration has an onset of five minutes peak of thirty and duration of two hours the half-life of ferocide is about thirty to sixty minutes though it can be increased in patients with renal impairment let’s move on to contraindications for the use

Of furosemide it’s contraindicated in hypersensitivity hepatic coma which is the altered state of consciousness as a result of liver failure as well as anuria which is the failure of the kidneys to produce urine when considering drug interactions ferocimide may have cross sensitivity with the use of thiazides and sulfonamides as well it can cause an increased

Risk of hypotension with hypertensives nitrates or alcohol liquid products that may contain alcohol should be avoided in patients with an alcohol intolerance furosemide causes increased risk of hypokalemia when used with other diuretics amphotericin b stimulant laxatives and corticosteroids it has a decreased effect when given at the same time as sucraphylate

Cholesteramine or cholestepole due to the nature of this diuretic many essential electrolytes vitamins and minerals are lost through increased urine output which can put the patient at risk for common adverse side effects these include dehydration hypocalcemia hypochloremia hypokalemia hypomagnesema hyponatremia hypovolemia and metabolic alkalosis as nursing

Students administering furosemide in our clinical settings we need to be aware of the nursing implications for this medication first we need to consider that the use of diuretics is associated with an increased risk for falls in older adults so we need to assess fall risk and implement fall prevention strategies before beginning this therapy we should assess for

Allergies to sulfonamides and should monitor our patient’s blood pressure before and during administration as well we should assess their skin for rash frequently during therapy discontinuing at the first sign of rash as it may be life-threatening finally we need to assess their fluid status this is by monitoring their daily weight their ins and out ratios the

Amount or location of edema their lung sounds skin turgor and mucous membranes thank you so much for your attention today in our presentation we hope you understand the role of furosemide and diuretics a bit more and are able to implement what you’ve learned today into your clinical settings

Transcribed from video
Medication Montage: Furosemide By Laura Couture