So, uh… does it work?
I stumbled into the weirdest thing recently, “researchers discover some very exciting new “is it really the fountain of youth? are we onto something here?” it’s all in the news now because it’s getting so… to try to live longer, billionaires anti-aging generally has a bad name. in anti-aging there are lots of charlatans. sorry. what researchers
Are actually trying to do is specifically, the chance you die from these very common diseases goes up. drives the disease. and if you stop this what he told me, and this took me a minute to wrap us die from spring from that damage – often in but if you could delay the damage somehow, you could also delay the diseases, right? and
And in 2014, dr. barzilai happened on the people with diabetes taking other drugs not metformin, and people without diabetes double the mortality – the number of on metformin that were diabetics, were more obese, the fact that people with diabetes who were taking metformin and second, the only people taking metformin
It’s not clear whether that whole “dying less” thing when you eat or drink, your blood transports in people with diabetes, these blood sugar levels can get too high and metformin helps control that. we have research on this going back decades to we know a lot less about how it may or may not work in people without diabetes
For anti-aging. already a cheap generic drug, which means there’s not as much incentive for pharmaceutical other studies show metformin does seem but to know for sure whether metformin can actually delay “a proper randomized trial where they give half the people metformin that i’m leading now. this is the tame study. tame
Stands for targeting aging with metformin. and the reason i’m doing that is not to repeat plan a study for the fda to repurpose a drug and push back the diseases that kill the most of us. but a drug that is already on the market and i get surprisingly emotional thinking about this topic. genuinely can’t think of anything
That i would want in the meantime, whether or not you wanna take metformin or i do boils down to our (not the tame trial, because it probably won’t be done for a while) the second is how urgent aging actually feels the third is how you weigh your perceived the first week of use. you feel early satiety, it also impacts
How your body responds to exercise. metformin, your muscle will have the same ok. would i have diarrhea for a would i opt in for that if i weren’t pretty sure it would work? so the people in the news right now who are taking metformin we don’t mind these side effects too much, and aging you know, i’ve been struggling a little
Bit because on the one hand, i really want to and on the other hand, i really don’t that’s how my calculation came out. i want to wait for more studies. but metformin isn’t the only option being studied. if we figure out that any option meaningfully 55 million people have alzheimers or other dementias.
Transcribed from video
Metformin, the big new "anti-aging" drug, explained By Cleo Abram