June 4, 2023

Presented by Elike G, Saskakibara M, and Gazaha N (Aug, 8th, 2022)

Hello everyone my name is nada today my group and i will cover the pharmacotherapeutics pharmacokinetics pharmacodynamics the nursing assessments and intervention of metopr law which is also known as low pressure indications for metoprolol the federal drug and administration fda approves use of metoprolol for the following therapeutic uses hypertension angina

Pectoris myocardial infarction cardiomyopathy hypertension also known as high blood pressure affects the heart and blood vessels a constant systolic and diastolic pressure of 140-90 mmhg and above is considered a high blood pressure angina pectoris is an acute chest pain the oxygen demand on the heart exceeds the supply and is caused by severe narrowing of the

Coronary arteries myocardial infarction also known as heart attack is the death of the heart muscle caused by blockage of the coronary artery one known cause of coronary embolism is atherosclerosis cardiomyopathy is the inflammation of the heart due to heart disease this results to decreased heart rate and contractility as the heart is unable to pump out and pump

In blood other indicated uses of metoprolol include migraine prophylaxis atrial fibrillation flutter some common side and adverse effects of metoprolol include postural hypotension bradycardia drowsiness depression heart failure bronchospasm bronchoconstriction malaise lethargy metoprolol increases the oxygen supply to the heart by decreasing peripheral resistance

Workload cardiac output metoprolol can help reduce death rate from post myocardial infarction lower blood pressure and reduce the frequency and severity of angina attack absorption takes in large intestine and 95 of therapeutic doses recovered in urine as unchanged form distribution happens very quickly between the blood and extravascular sites and only one to

Two percent of the drug stays in the blood metoprolol is metabolized in the liver by enzyme is called cyp2d6 elimination is occurred in the liver and excreted as urine 95 of drug is recovered in urine and 5 excreted as unchanged drug via kidneys metoprolol starts to work in the body within one hour taken by orally and 20 minutes by iv route the peak effect of the

Medication is one to two hours after administration concentration of metoprolol is decreased to half in three to seven hours metoprolol is effective about six to eight hours mostly prescribed once a day let’s learn how to take metoprelol safely metoprolol is administered by either oral or intravenous route immediate and extended release tablet available for oral

Route remember not to break or crash extended release tablet and check the pulse before administrating medication there are so many drugs interactions with metoprolol other heart or blood pressure medications epinephrine antidepressant monoamine oxidase inhibitors taking monoamine oxidase inhibitors and metoprolol at the same time can add the effect of medication

And causes headache and slowing heart rate sick sinus syndrome causes abnormal heart rice metoprolol can cause the client faint or unable to pump blood normally by slowing heart rate and blood pressure metroprolol slows down the heart rate and blood pressure if a client with heart failure or an av block takes metoprolol it can cause their disease progression to

Worsen withdrawal syndrome can commonly happen using metoprolol the client need to be educated not to stop taking metoprolol abruptly pregnant women and mother who’s breastfeeding their baby should be careful using metoprolol because metoprolol can cross the placenta and could be contained in the breast milk child from zero to five years olds can’t take metoprolol

65 years old and older generally take more time to absorb this medication in the body therefore proper education and close monitoring is needed for this age group metoprolol is a selected selective beta-1 adrenergic receptor blocker it acts by blocking the effect of noradrenaline on the beta-1 receptor on the cardiac myocyte cell causing a decrease in heart rate

And contractility which decrease the myocardial o2 demands a complete health history including drug history and allergies must be obtained when considering giving metoprolol also baseline vital signs cardiac and urinary output must be obtained lastly assessing for any existing respiratory disease as a nurse we should monitor for vital sign blood pressure pulse and

Ecg we should also monitor the patient for shortness of breath adverse effects such as orthostatic hypotension fatigue weakness and drowsiness nurses should monitor for pulmonary edema fluid intake and output lastly body weight should be monitor mr john please do not stop taking this medication abruptly do not cut crush or chew tablet do not skip a dose or double

Up a mistos and please report any difficulty breathing in any side effect immediately you

Transcribed from video
Metoprolol(Lopressor) By Grace E