Htr to a hdr to a stands for five hydroxy to mean receptor to a 5-hydroxytryptamine receptor to a is one of the receptors for serotonin mutations in this gene are associated with schizophrenia an obsessive-compulsive disorder and are also associated with response to the antidepressant citalopram in patients with major depressive disorder also known as m d d mdd
Patients who also have a mutation and intron two of this gene show a significantly reduced response to citalopram as this antidepressant down regulates expression of this gene htr qu a also functions as a receptor for various drugs and psychoactive substances including mescaline psilocybin 1-2 5 dimethyl c4i auto phenyl 2 amino propane also known as do i and
Lysergic acid diethylamide also known as lsd it also effects normal activity perception cognition and mood and a role in regulation of behavior including responses to angiogenic situations and psychoactive substances ht r qu a is involved in intestinal smooth muscle contraction and may play a role in arterial vasoconstriction the molecular functions for ht r 2a
Are 1-4 i odo to 5 dimethyl see phenyl propane to amine binding serotonin binding drug binding and serotonin receptor activity the biological processes for ht r 2a are activation of phospholipase c activity arteries smooth muscle contraction cell death detection of mechanical stimulus involved in sensory perception of pain memory negative regulation of synaptic
Transmission glutamatergic phospholipase c activating serotonin receptor signaling pathway positive regulation of earth 1 and earth to cascade positive regulation of glycolytic process positive regulation of peptidyl tyrosine phosphorylation positive regulation of vasoconstriction regulation of behavior regulation of hormone secretion response to drug sleep aging
Behavioral response to cocaine cellular calcium ion homeostasis detection of temperature stimulus involved and sensory perception of pain negative regulation of potassium ion transport phosphatidyl inositol 3 kinase signaling positive regulation of cell proliferation positive regulation of fat cell differentiation positive regulation of map m ap kinase activity
Positive regulation of phosphatidyl enos ital biosynthetic process protein localization – cytoskeleton regulation of dopamine secretion release of sequestered calcium ion into cytosol serotonin receptor signaling pathway synaptic transmission and urinary bladder smooth muscle contraction drugs used for the proper functioning of htr – ar acepromazine amasau pride
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Bio fixing trazadone try mit / mean yohimbine ziprasidone and zoo clos pim fix all ht r qu a interacts with the following genes mp dz i n ad l m p p3 p rd x 6 d l g 4d l g 1c a sk a pb a 1m ag i 2 g r m 2 and d rd two variants at the gene encoding for 5-hydroxytryptamine also known as serotonin receptor to a or h tr to a have been associated with many psychiatric
Disorders such as schizophrenia mood disorders attention deficit hyperactivity disorder suicide anxiety disorders obsessive-compulsive disorder eating disorders and alzheimer’s disease diseases associated with this gene are cystic fibrosis obstructive sleep apnea cirrhosis coronary artery spasm prinzmetal angina if you have any concerns about this gene contact
A practitioner who is familiar with epigenetics and nutrigenomics we hope that you’ve enjoyed this snp bit
Transcribed from video
What is HTR2A? By MTHFRSupport official